The sensitivity of mass detection algorithms decreases as the
density of the breast increases. In order to deal with this
problem an initial pre-processing of the mammogram can be done
estimating the density of the breast. This pre-processing may be
performed manually or, as shown in Chapter
automatically. In both cases, this parameter is known before the
detection algorithm begins.
Once the breast density is known, the question is how to introduce this information into the algorithm. Obviously, there is not an unique solution, and actually this will be algorithm-dependent. A way forward could be fine-tuning the parameters of the algorithm depending on the tissue type.
In our case, however, this information is easier to introduce. We
cluster both RoIs databases (the first one containing only masses
for template creation and the second one containing masses and
normal tissue for false positive reduction) according to the
breast density parameter. In order to avoid the need of manual
intervention, this tissue classification step is automatically
done using the automatic classification approach analyzed in
Chapter . In Section
we
compare the obtained results using this algorithm and the ones
obtained using the experts manual classification. Note that this
cannot be done with the MIAS database as there is not a
significant difference between both classification (only one of
the forty mammograms with masses was classified in different
BIRADS categories using the manual annotations and the automatic
algorithm).